MyBioSource.com's COIL Antibody (Center) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The COIL Antibody (Center) was generated using Coilin, and p80-coilin as the antigen and it reacts with Human.
Description
The protein encoded by this gene is an integral component
of Cajal bodies (also called coiled bodies). Cajal bodies are
nuclear suborganelles of varying number and composition that are
involved in the post-transcriptional modification of small nuclear
and small nucleolar RNAs. The N-terminus of the coilin protein
directs its self-oligomerization while the C-terminus influences
the number of nuclear bodies assembled per cell. Differential
methylation and phosphorylation of coilin likely influences its
localization among nuclear bodies and the composition and assembly
of Cajal bodies. This gene has pseudogenes on chromosome 4 and
chromosome 14